| Amplifying the manganese scavenging potential of Streptococcus zooepidemicus to reactive oxygen species during production of hyaluronic acid. | |
| | |
MedLine Citation:
|
PMID: 15468818 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Streptococcus zooepidemicus (SZ) is an aerotolerant bacteria and its ability to survive under reactive oxidant challenge raises the question of the existence of a defense system. Thus growth, hyaluronic acid (HA) and hydrogen peroxide (H2O2) production by SZ in the presence of increasing concentration of Mn2+ were studied. The results suggested that the tested strain supported growth and HA production in cultures treated with 1 and 10 mM of Mn2+ regardless of H2O2 presence in the medium. This showed that SZ have acquired elaborate defense mechanisms to scavenge oxygen toxicity and thus protect cells from direct and indirect effect of this radical. In contrast, cells treated with 25 mM Mn2+ were sensitive, in which, the HA production was reduced considerably. Thus showing that the oxygen scavenger systems of the cells may be fully saturated at this concentration. |
| | |
Authors:
|
M D Mashitah; H Masitah; K B Ramachandran |
Related Documents
:
|
6657918 - The radiation response of hypoxic cells in emt6 spheroids in suspension culture does mo... 5459938 - Undamped oscillations of pyridine nucleotide and oxygen tension in chemostat cultures o... 392268 - Cultivation requirements for treponema pallidum, mycobacterium leprae and other microbi... 1958348 - Effects of alloxan and reducing agents on macrophages in culture. 12786978 - Removal of psa from ncam affects the survival of magnocellular vasopressin- and oxytoci... 7542408 - Enhancement of the activity of bleomycin by cysteamine in a micronucleus assay in g0 hu... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Medical journal of Malaysia Volume: 59 Suppl B ISSN: 0300-5283 ISO Abbreviation: Med. J. Malaysia Publication Date: 2004 May |
Date Detail:
|
Created Date: 2004-10-07 Completed Date: 2004-12-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0361547 Medline TA: Med J Malaysia Country: Malaysia |
Other Details:
|
Languages: eng Pagination: 59-60 Citation Subset: IM |
Affiliation:
|
Department of Chemical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Dose-Response Relationship, Drug Free Radical Scavengers / metabolism* Humans Hyaluronic Acid / biosynthesis* Hydrogen Peroxide / metabolism* Magnesium / pharmacology* Reactive Oxygen Species / metabolism* Streptococcus equi / drug effects*, metabolism Superoxide Dismutase / physiology |
| Chemical | |
Reg. No./Substance:
|
0/Free Radical Scavengers; 0/Reactive Oxygen Species; 7439-95-4/Magnesium; 7722-84-1/Hydrogen Peroxide; 9004-61-9/Hyaluronic Acid; EC 1.15.1.1/Superoxide Dismutase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Characterization of collagen/chitosan films for skin regenerating scaffold.
Next Document: Mechanical properties of HDPE/UHMWPE blends: effect of filler loading and filler treatment.