| Amplification of mitochondrial DNA fragments from ancient human teeth and bones | |
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MedLine Citation:
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PMID: 2113826 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We extracted and visualized DNA from ancient human teeth and bones of 150 to 5,500 years B.P. from three deposits from the south of France. The DNA extracted was used as template for PCR with specific primers corresponding to a portion of the human mitochondrial genome. In our samples, we have amplified a specific DNA fragment of 121 bp which, in the case of one bone of 150 years B.P. has been cloned and sequenced. We show that this sequence is identical to the homologous region of human mitochondrial DNA. The striking implications of this new method for archaeological and paleontological studies are exposed. |
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Authors:
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C Hänni; V Laudet; M Sakka; A Bègue; D Stéhelin |
Publication Detail:
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Type: English Abstract; Historical Article; Journal Article |
Journal Detail:
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Title: Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie Volume: 310 ISSN: 0764-4469 ISO Abbreviation: C. R. Acad. Sci. III, Sci. Vie Publication Date: 1990 |
Date Detail:
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Created Date: 1990-08-08 Completed Date: 1990-08-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8503078 Medline TA: C R Acad Sci III Country: FRANCE |
Other Details:
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Languages: fre Pagination: 365-70 Citation Subset: IM; Q |
Affiliation:
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Laboratoire de Morphologie évolutive, Muséum d'Histoire naturelle, Paris. |
Vernacular Title:
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Amplification de fragments d'ADN mitochondrial à partir de dents et d'os humains anciens. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Base Sequence Bone and Bones / ultrastructure* DNA, Mitochondrial / isolation & purification* Fossils History, Ancient Humans Molecular Sequence Data Nucleic Acid Amplification Techniques* Paleodontology* Polymerase Chain Reaction Tooth / ultrastructure* |
| Chemical | |
Reg. No./Substance:
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0/DNA, Mitochondrial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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