Document Detail


Amplification of G-quadruplex DNAzymes using PCR-like temperature cycles for specific nucleic acid and single nucleotide polymorphism detection.
MedLine Citation:
PMID:  21116529     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A nucleic acid sensor, based on the amplified formation of G-quadruplex DNAzymes by polymerase chain reaction (PCR)-like temperature cycles, was developed. This "turn-on" process allowed effective detection of specific nucleic acid targets and identification of single nucleotide polymorphisms (SNPs).
Authors:
Na Wang; De-Ming Kong; Han-Xi Shen
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Publication Detail:
Type:  Journal Article     Date:  2010-11-29
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  47     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  1728-30     Citation Subset:  IM    
Affiliation:
Key Laboratory of Functional Polymer Materials, Ministry of Education, Nankai University, Tianjin, 300071, People's Republic of China. kongdem@nankai.edu.cn.
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