Document Detail

Amphotericin B-induced cutaneous leucocytoclastic vasculitis: case report.
MedLine Citation:
PMID:  18076602     Owner:  NLM     Status:  MEDLINE    
A 37-year-old female patient was diagnosed with ulcerative colitis 8 months ago and medical treatment with oral azathioprine, low-dose corticosteroids and 5-ASA was started. Following 3 months without any symptoms, the patient had total colectomy and ileostomy. After this period, liposomal amphotericin B (3 mg kg(-1) day(-1)) was given with the diagnosis of probable fungal infection. Palpable purpuric skin lesions on the anterior surface of both legs appeared on the 55th day of amphotericin B treatment. Histological examination of a skin biopsy was consistent with leucocytoclastic vasculitis. We present a case of cutaneous leucocytoclastic vasculitis in which amphotericin B might presumably be the aetiological factor.
A Atahan Cagatay; Ozer Taranoglu; Nilufer Alpay; Fatih Tufan; Asli Karadeniz; Mahir Kapmaz; Nesimi Buyukbabani
Publication Detail:
Type:  Case Reports; Letter    
Journal Detail:
Title:  Mycoses     Volume:  51     ISSN:  0933-7407     ISO Abbreviation:  Mycoses     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-13     Completed Date:  2008-03-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8805008     Medline TA:  Mycoses     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  81-2     Citation Subset:  IM    
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MeSH Terms
Amphotericin B / adverse effects*,  therapeutic use
Mycoses / drug therapy
Skin Diseases / pathology*
Vasculitis / pathology*
Reg. No./Substance:
1397-89-3/Amphotericin B

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