Document Detail

Amphotericin B-deoxycholate overdose due to administration error in pediatric patients.
MedLine Citation:
PMID:  18324499     Owner:  NLM     Status:  MEDLINE    
Due to the similarity of their generic names, the use of amphotericin B-deoxycholate and liposomal amphotericin B could cause confusion in daily practice. We report two cases of amphotericin B-deoxycholate overdose in infants due to administration errors which raises the issue that the use of this antifungal agent should be questioned because of its severe side effects.
Susanne Groeneveld; Paul E Verweij; Louis Van't Hek; Jos P M Bökkerink; Adilia Warris
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Medical mycology     Volume:  46     ISSN:  1369-3786     ISO Abbreviation:  Med. Mycol.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-07     Completed Date:  2008-08-13     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  9815835     Medline TA:  Med Mycol     Country:  England    
Other Details:
Languages:  eng     Pagination:  185-7     Citation Subset:  IM    
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MeSH Terms
Amphotericin B / administration & dosage,  adverse effects,  poisoning*,  therapeutic use
Antifungal Agents / administration & dosage,  poisoning*
Chemistry, Pharmaceutical
Deoxycholic Acid / administration & dosage,  adverse effects,  poisoning*
Drug Combinations
Drug Overdose
Fatal Outcome
Medication Errors*
Reg. No./Substance:
0/Antifungal Agents; 0/Drug Combinations; 005990WHZZ/Deoxycholic Acid; 7XU7A7DROE/Amphotericin B; 87687-70-5/amphotericin B, deoxycholate drug combination

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