Document Detail


Amperometric biosensor based on diamond paste for the enantioanalysis of l-lysine.
MedLine Citation:
PMID:  22417875     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
An amperometric biosensor was proposed for the enantioanalysis of l-lysine. The biosensor is based on the impregnation of l-lysine oxidase in diamond paste. The potential used for the determination of l-lysine was 650mV. The biosensor exhibited a linear concentration range between 1 and 100nmol/L with a limit of detection of 4pmol/L. The selectivity of the biosensor is high over other amino acids, such as l-serine, l-leucine, l-aspartic acid, l-glutamic acid, histamine, glycine. The proposed biosensor can be applied for the determination of l-lysine in serum samples and pharmaceutical compounds.
Authors:
Raluca-Ioana Stefan-van Staden; R'afat Mahmoud Nejem; Jacobus Frederick van Staden; Hassan Y Aboul-Enein
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-24
Journal Detail:
Title:  Biosensors & bioelectronics     Volume:  -     ISSN:  1873-4235     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-3-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001289     Medline TA:  Biosens Bioelectron     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier B.V. All rights reserved.
Affiliation:
Laboratory of Electrochemistry and PATLAB Bucharest, National Institute of Research for Electrochemistry and Condensed Matter, 202 Splaiul Independentei Str., 060021, Bucharest 6, Romania.
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