Document Detail

Amoxicillin plus clavulanic acid in the treatment of recurrent urinary tract infections.
MedLine Citation:
PMID:  6561953     Owner:  NLM     Status:  MEDLINE    
Forty-four patients (43 female, 1 male), all with a history of recurrent urinary tract infections, were treated with 250 mg of amoxicillin plus 125 mg of clavulanic acid (one tablet of Augmentin) every 8 h for 7 days. The microbiological cure rates were 84% 1 week after the end of treatment and 67% 1 month later. Side effects, which were reported by 20% of the patients, were mild and in no case caused interruption of treatment. In view of the increasing trend in resistance to agents commonly used for the treatment of urinary tract infections in outpatients, the combination of amoxicillin and clavulanic acid may now be considered a first-line drug in patients with recurrent urinary tract infections.
W Brumfitt; J M Hamilton-Miller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Antimicrobial agents and chemotherapy     Volume:  25     ISSN:  0066-4804     ISO Abbreviation:  Antimicrob. Agents Chemother.     Publication Date:  1984 Feb 
Date Detail:
Created Date:  1984-05-04     Completed Date:  1984-05-04     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0315061     Medline TA:  Antimicrob Agents Chemother     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  276-8     Citation Subset:  IM    
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MeSH Terms
Amoxicillin / adverse effects,  therapeutic use*
Amoxicillin-Potassium Clavulanate Combination
Clavulanic Acids / adverse effects,  therapeutic use*
Drug Combinations / adverse effects,  therapeutic use
Middle Aged
Penicillin Resistance
Urinary Tract Infections / drug therapy*,  microbiology
Reg. No./Substance:
0/Clavulanic Acids; 0/Drug Combinations; 26787-78-0/Amoxicillin; 74469-00-4/Amoxicillin-Potassium Clavulanate Combination

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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