Document Detail

Amoxicillin and diaper dermatitis.
MedLine Citation:
PMID:  3049689     Owner:  NLM     Status:  MEDLINE    
Multiple skin sites and the gastrointestinal tract of 57 infants with otitis media were cultured quantitatively for Candida albicans before and after antibiotic therapy. Ten days of systemic therapy with amoxicillin was associated with a twofold increase in the recovery of C. albicans from the rectum and skin. Infants who developed diaper dermatitis had a significant increase in the number of C. albicans organisms recovered from these sites. We conclude that the use of amoxicillin increases the risk for developing diaper dermatitis.
P J Honig; B Gribetz; J J Leyden; K J McGinley; L A Burke
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  19     ISSN:  0190-9622     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1988-11-17     Completed Date:  1988-11-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  275-9     Citation Subset:  IM    
Children's Hospital, Philadelphia, Philadelphia 19104.
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MeSH Terms
Administration, Oral
Amoxicillin / administration & dosage,  therapeutic use*
Candida albicans / isolation & purification
Candidiasis, Cutaneous*
Child, Preschool
Diaper Rash / etiology*
Intestines / microbiology
Otitis Media / drug therapy
Perineum / microbiology
Rectum / microbiology
Risk Factors
Skin / microbiology
Reg. No./Substance:

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