| Amoebic dysentery. | |
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MedLine Citation:
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PMID: 21477391 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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INTRODUCTION: Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica. It is transmitted in areas where poor sanitation allows contamination of drinking water and food with faeces. In these areas, up to 40% of people with diarrhoea may have amoebic dysentery. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of drug treatments for amoebic dysentery in endemic areas? We searched: Medline, Embase, The Cochrane Library, and other important databases up to April 2010 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: We found 6 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. CONCLUSIONS: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: diiodohydroxyquinoline (iodoquinol), diloxanide, emetine, metronidazole, nitazoxanide, ornidazole, paromomycin, secnidazole, and tinidazole. |
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Authors:
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Nicole M Mackey-Lawrence; William Arthur Petri |
Publication Detail:
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Type: Journal Article Date: 2011-01-13 |
Journal Detail:
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Title: Clinical evidence Volume: 2011 ISSN: 1752-8526 ISO Abbreviation: Clin Evid (Online) Publication Date: 2011 |
Date Detail:
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Created Date: 2011-04-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101294314 Medline TA: Clin Evid (Online) Country: England |
Other Details:
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Languages: eng Pagination: - Citation Subset: IM |
Affiliation:
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University of Virginia, Charlottesville, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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