|Amniotic fluid lecithin/sphingomyelin ratio in complicated pregnancies.|
|PMID: 1155519 Owner: NLM Status: MEDLINE|
|Amniotic fluid (AF) lecithin/sphingomyelin (L/S) rations were obtained in 223 pregnancies. Gestations complicated by maternal diabetes (71), vascular disease (50), and fetal growth retardation (47) were included. Elevated L/S ratios at 34 to 36 weeks' gestation were observed to accompany maternal vascular disease; higher rat;os were also related to fetal sex (female) and race (black). Declining L/S rations were observed in 14 of 35 diabetic patients studied serially (40 per cent) and were accompanied by increased perinatal morbidity and deaths. These data suggest an urgent need for further studies concerning the clinical usefulness of a serial decline in the L/S ration as a predictor of fetal compromise.|
|D Dyson; M Blake; G Cassady|
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|Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.|
|Title: American journal of obstetrics and gynecology Volume: 122 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1975 Jul|
|Created Date: 1975-11-01 Completed Date: 1975-11-01 Revised Date: 2006-11-15|
Medline Journal Info:
|Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES|
|Languages: eng Pagination: 772-81 Citation Subset: AIM; IM|
|APA/MLA Format Download EndNote Download BibTex|
African Continental Ancestry Group
Amniotic Fluid / analysis*
Asphyxia Neonatorum / epidemiology
Creatinine / analysis
Estrogens / blood
European Continental Ancestry Group
Fetus / physiology*
Infant, Newborn, Diseases
Phosphatidylcholines / analysis*
Pregnancy in Diabetics
Respiratory Distress Syndrome, Newborn / epidemiology
Sphingomyelins / analysis*
|0/Estrogens; 0/Phosphatidylcholines; 0/Sphingomyelins; 60-27-5/Creatinine|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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