Document Detail

Amniotic fluid lecithin/sphingomyelin ratio in complicated pregnancies.
MedLine Citation:
PMID:  1155519     Owner:  NLM     Status:  MEDLINE    
Amniotic fluid (AF) lecithin/sphingomyelin (L/S) rations were obtained in 223 pregnancies. Gestations complicated by maternal diabetes (71), vascular disease (50), and fetal growth retardation (47) were included. Elevated L/S ratios at 34 to 36 weeks' gestation were observed to accompany maternal vascular disease; higher rat;os were also related to fetal sex (female) and race (black). Declining L/S rations were observed in 14 of 35 diabetic patients studied serially (40 per cent) and were accompanied by increased perinatal morbidity and deaths. These data suggest an urgent need for further studies concerning the clinical usefulness of a serial decline in the L/S ration as a predictor of fetal compromise.
D Dyson; M Blake; G Cassady
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  122     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1975 Jul 
Date Detail:
Created Date:  1975-11-01     Completed Date:  1975-11-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  772-81     Citation Subset:  AIM; IM    
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MeSH Terms
African Continental Ancestry Group
Amniotic Fluid / analysis*
Asphyxia Neonatorum / epidemiology
Creatinine / analysis
Estrogens / blood
European Continental Ancestry Group
Fetus / physiology*
Gestational Age
Infant, Newborn
Infant, Newborn, Diseases
Phosphatidylcholines / analysis*
Pregnancy Complications
Pregnancy in Diabetics
Respiratory Distress Syndrome, Newborn / epidemiology
Respiratory System
Sex Factors
Sphingomyelins / analysis*
Reg. No./Substance:
0/Estrogens; 0/Phosphatidylcholines; 0/Sphingomyelins; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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