Document Detail


Amniotic fluid erythropoietin predicts fetal distress in Rh-immunized pregnancies.
MedLine Citation:
PMID:  2492765     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Repeated amniotic fluid erythropoietin measurements in 23 Rh-immunized pregnancies were done to evaluate erythropoietin levels of amniotic fluid as an indicator of fetal distress (umbilical artery, pH 7.14 or less, or 1-minute Apgar score of 4 or less). Amniotic fluid erythropoietin levels did not vary significantly between 168 and 273 gestational days in the pregnancies without fetal distress. Increasing levels of amniotic fluid erythropoietin predicted highly reliably severe fetal distress at birth. Whether erythropoietin levels of amniotic fluid can also predict fetal distress in other pathologic pregnancies needs further study.
Authors:
P E Voutilainen; J A Widness; G K Clemons; R Schwartz; K A Teramo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  160     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1989 Feb 
Date Detail:
Created Date:  1989-03-23     Completed Date:  1989-03-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  429-34     Citation Subset:  AIM; IM    
Affiliation:
Department I of Obstetrics and Gynecology, University of Helsinki, Finland.
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MeSH Terms
Descriptor/Qualifier:
Amniotic Fluid / analysis*
Bilirubin / analysis
Erythropoietin / analysis*,  blood
Female
Fetal Blood / analysis
Fetal Distress / diagnosis*
Humans
Infant, Newborn
Pregnancy
Pregnancy Complications, Hematologic / metabolism*
Rh Isoimmunization / metabolism*
Grant Support
ID/Acronym/Agency:
HD-11343/HD/NICHD NIH HHS; NHLBI-22469/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
11096-26-7/Erythropoietin; 635-65-4/Bilirubin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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