Document Detail

Amniotic fluid embolism with haemostasis complications: primary fibrinogenolysis or disseminated intravascular coagulation?
MedLine Citation:
PMID:  15170398     Owner:  NLM     Status:  MEDLINE    
Amniotic fluid embolism (AFE) is characterized by the passage of amniotic fluid (AF) into the maternal circulation during or just after childbirth. AFE is a rare disorder occurring in 1/8,000 to 1/80,000 deliveries but with a maternal morbidity ranging from 26% in a recent report to 86% in earlier ones. In patients who survive, AFE may affect coagulation resulting in severe bleeding. While disseminated intravascular coagulation (DIC) is usually seen in such cases, we reported a case of AFE in which the hemostatic abnormalities were compatible with primary fibrinogenolysis rather than with DIC.
C Biron-Andréani; E Morau; J-F Schved; B Hédon; H Dechaud
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pathophysiology of haemostasis and thrombosis     Volume:  33     ISSN:  1424-8832     ISO Abbreviation:  Pathophysiol. Haemost. Thromb.     Publication Date:    2003 May-Jun
Date Detail:
Created Date:  2004-06-01     Completed Date:  2005-03-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101142710     Medline TA:  Pathophysiol Haemost Thromb     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  170-1     Citation Subset:  IM    
Copyright Information:
Copyright 2003 S. Karger AG, Basel
Laboratoire d'Hématologie, Centre Hospitalier Universitaire, Montpellier, France.
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MeSH Terms
Blood Coagulation Disorders / diagnosis*,  etiology
Blood Component Transfusion
Diagnosis, Differential
Disseminated Intravascular Coagulation / diagnosis*,  etiology
Embolism, Amniotic Fluid / blood,  complications*,  diagnosis
Hemorrhage / diagnosis,  etiology,  therapy
Treatment Outcome

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