Document Detail


Amniotic fluid embolism: a rare cause of acute left-sided heart failure.
MedLine Citation:
PMID:  17205922     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY DESIGN AND SETTING: Two case reports, University Hospital of Antwerp, tertiary referral hospital of the University of Antwerp, Edegem, Belgium. METHODS AND RESULTS: Two women were transferred to our hospital because of acute cardiorespiratory failure due to amniotic fluid embolism during the peripartal period. Both required intensive supportive treatment and invasive monitoring. Haemodynamic data revealed primary left ventricular failure confirming the clinical picture of cardiogenic pulmonary oedema. Review of the literature provides data that do not support obstruction of the pulmonary vasculature by amniotic fluid as the only primary pathophysiological event. However, despite several case reports stressing left ventricular failure as the dominant clinical event, pathophysiological mechanisms are merely speculative. CONCLUSIONS: The diagnosis of amniotic fluid embolism remains a clinical challenge, but can be supported by the presence of amniotic cells in the pulmonary artery, aspirated through a pulmonary artery catheter. The treatment is still not causative but supportive. An overview of cases in the literature with predominant left heart failure during amniotic fluid embolism is given.
Authors:
Wim Huybrechts; Philippe G Jorens; Yves Jacquemyn; Cecile Colpaert; Christiaan Vrints; Viviane Conraads
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta cardiologica     Volume:  61     ISSN:  0001-5385     ISO Abbreviation:  Acta Cardiol     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2007-01-08     Completed Date:  2007-02-22     Revised Date:  2009-06-11    
Medline Journal Info:
Nlm Unique ID:  0370570     Medline TA:  Acta Cardiol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  643-9     Citation Subset:  IM    
Affiliation:
Department of Cardiology, University Hospital of Antwerp, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Embolism, Amniotic Fluid / pathology,  physiopathology*
Female
Heart Failure / etiology*,  pathology,  physiopathology*
Humans
Pregnancy

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