Document Detail


Amniotic fluid beta-endorphin levels and labor.
MedLine Citation:
PMID:  2952913     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To define the relationship between amniotic fluid concentrations of beta-endorphin immunoreactivity and onset of parturition, we measured this opioid in samples obtained during cesarean section at term. A total of 27 women were studied, 14 without labor and 13 in early labor. Mean (+/- SE) amniotic fluid beta-endorphin levels were significantly lower in patients in labor than in those not in labor (3.2 +/- 0.05 versus 8.4 +/- 1.0 fmol/mL). The mean beta-endorphin level (21.1 +/- 4.2 fmol/mL) in other amniotic fluid samples obtained during the second trimester of pregnancy was significantly higher than mean values at term. These differences in amniotic fluid beta-endorphin levels may support the theory of an opioid mechanism involved in parturition.
Authors:
G D Kofinas; A D Kofinas; M Pyrgerou; F I Reyes
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  69     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-06-19     Completed Date:  1987-06-19     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  945-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Amniotic Fluid / analysis*
Cesarean Section
Chromatography, Affinity
Endorphins / analysis*
Female
Gestational Age
Humans
Labor Onset*
Labor, Obstetric*
Pregnancy
Pregnancy Trimester, Second
Radioimmunoassay
beta-Endorphin
Chemical
Reg. No./Substance:
0/Endorphins; 60617-12-1/beta-Endorphin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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