| Amniotic fluid beta-2-microglobulin in normal and complicated pregnancies. Correlation with gestational age, creatinine concentration and L/S ratio. | |
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MedLine Citation:
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PMID: 6178654 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The beta-2-microglobulin concentrations in 127 aminotic fluid samples, obtained during weeks 32-42 of normal pregnancies (n = 58) and complicated pregnancies (n = 69), were measured and correlated with gestational weeks, amniotic fluid creatinine concentrations and L/S ratios. A significant (p less than 0.001) decrease of beta-2-microglobulin concentration occurred from week 32 to 34 of normal pregnancies, after which the beta-2-microglobulin level was unchanged. There were no significant correlations between beta-2-microglobulin concentrations and amniotic fluid creatinine concentrations of LK/S ratios. The beta-2-microglobulin content was elevated in samples obtained from diabetic and toxemic pregnancies. Measurement of beta-2-microglobulin in amniotic fluid seems to be of limited value for determining fetal age, but it may be useful in estimating fetal renal maturity. |
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Authors:
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J Puolakka; P Ylöstalo; R Tuimala; J Haapalahti; P A Järvinen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gynecologic and obstetric investigation Volume: 13 ISSN: 0378-7346 ISO Abbreviation: Gynecol. Obstet. Invest. Publication Date: 1982 |
Date Detail:
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Created Date: 1982-09-10 Completed Date: 1982-09-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7900587 Medline TA: Gynecol Obstet Invest Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 129-34 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amniotic Fluid
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analysis* Beta-Globulins / analysis* Creatinine / analysis* Female Fetal Organ Maturity Gestational Age Humans Kidney / embryology Phosphatidylcholines / analysis Pregnancy* Pregnancy Complications / metabolism* Sphingomyelins / analysis beta 2-Microglobulin / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Beta-Globulins; 0/Phosphatidylcholines; 0/Sphingomyelins; 0/beta 2-Microglobulin; 60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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