Document Detail

Amniotic fluid arborization in the diagnosis of previable preterm premature rupture of membranes.
MedLine Citation:
PMID:  22523873     Owner:  NLM     Status:  In-Process    
OBJECTIVE: To determine the accuracy of using amniotic fluid arborization to diagnose preterm premature rupture of membranes (PPROM) in the second trimester using specimens collected from the vaginal pool.
STUDY DESIGN: Women presenting for pregnancy termination between 14 and 22 weeks' gestation were enrolled. At the time of termination, amniotic fluid samples were collected directly from the amniotic sac and from the vaginal pool, air dried and examined for arborization.
RESULTS: Arborization was detected in 51/59 (86.4%) samples collected from the amniotic sac and 41/59 (69.5%) samples collected from the vaginal pool. The sensitivity and specificity in detecting arborization in fluid collected by swabbing the vagina was 0.69 and 0.98, respectively (positive predictive value 0.98%, negative predictive value 0.76).
CONCLUSION: While the presence of arborization in samples collected from the vaginal pool is predictive of PPROM in the second trimester, the absence of arborization should not rule out the diagnosis if there is strong clinical suspicion.
Shera Sugibayashi; Tod Aeby; David Kim; Bliss Kaneshiro
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  57     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:    2012 Mar-Apr
Date Detail:
Created Date:  2012-04-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  136-40     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Hawaii, Honolulu, USA.
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