Document Detail

Amnion-chorion separation after 17 weeks' gestation.
MedLine Citation:
PMID:  10576194     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the cause of and perinatal outcomes of amnion-chorion separation that is apparent sonographically after 17 weeks' gestation. METHODS: We searched our ultrasound database over 7 years for information on pregnant women who had live fetuses and complete separation between amnion and chorion that persisted beyond 17 weeks' gestation. For inclusion in the study, the women had to have amnion separated from chorion on at least three sides of the gestational sac. Medical records were reviewed for whether women had amniocenteses, results of the amniocenteses, and outcomes of the pregnancies. RESULTS: Of 15 pregnant women with live fetuses, ten had amniocenteses before identification of amnion-chorion separation and five did not. Three had fetuses with Down syndrome, two of whom had amnion-chorion separation evident before amniocentesis, and all three had other sonographic findings suggestive of aneuploidy. Three fetuses died. The other pregnancies were complicated by one or more adverse events, including two fetuses with growth restriction, five preterm deliveries, two with oligohydramnios, and one with abruptio placentae. Five infants were delivered at term and are alive and well. Overall, ten of 15 pregnancies resulted in live newborns, one of whom had Down syndrome. CONCLUSION: Complete amnion-chorion separation that persisted after 17 weeks' gestation is associated with a variety of adverse perinatal outcomes, including aneuploidy.
B Bromley; T D Shipp; B R Benacerraf
Related Documents :
1932744 - Prenatal diagnosis of neonatal alloimmune thrombocytopenia using allele-specific oligon...
1820774 - First-trimester diagnosis of hunter syndrome: very low iduronate sulphatase activity in...
12951884 - Obstetric outcome of excessively overgrown fetuses (> or = 5000 g): a case-control study.
8267804 - Progressive pulmonary stenosis in the fetus: two case reports.
25369724 - Sociocultural factors of teenage pregnancy in latino communities: preparing social work...
25099604 - Cardiovascular events in pregnancy with hypertrophic cardiomyopathy.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  94     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1999 Dec 
Date Detail:
Created Date:  1999-12-09     Completed Date:  1999-12-09     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1024-6     Citation Subset:  AIM; IM    
Department of Obstetrics & Gynecology, Massachusetts General Hospital, Brigham & Women's Hospital, Harvard Medical School, Boston, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Extraembryonic Membranes* / ultrasonography
Pregnancy Complications*
Pregnancy Outcome*
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Retrospective Studies
Ultrasonography, Prenatal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Predicting the risk of cystic fibrosis with echogenic fetal bowel and one cystic fibrosis mutation.
Next Document:  Immunohistochemical localization of the prostaglandin E subtype-1 receptor in cytokine-stimulated an...