Document Detail

Amniocentesis, maternal psychopathology and prenatal representations of attachment: a prospective comparative study.
MedLine Citation:
PMID:  22848599     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The aim of the study was to characterize the maternal dimensions of anxiety, depression and prenatal attachment in women undergoing an amniocentesis.
METHODOLOGY/PRINCIPAL FINDINGS: A prospective observational study was conducted. Women were referred to early amniocentesis for increased nuchal translucency, elevated biochemical markers or advanced maternal age. All participants had 3 prenatal (16-18, 20-24, 30-34 weeks of gestation) and one postnatal (30-45 days) interviews reviewing for demographic, medical, and psychiatric information (STAI State-Trait Anxiety Inventory; EPDS: Edinburgh Postnatal Depression Scale; IRMAG: Interview of Maternal Representations of Attachment during pregnancy). We investigated 232 pregnant women who undergone an amniocentesis compared with 160 pregnant controls. Following the procedure, the amniocentesis group experienced transiently significantly higher levels of state-anxiety on the STAI (44.6 vs. 39.3) and depression as measured by the EPDS (9.4 vs. 6.3) than the controls. Overall in both groups, the maternal representations of attachment were well integrated and balanced, but the amniocentesis group experienced significantly more mother-directed representations.
CONCLUSIONS/SIGNIFICANCE: Amniocentesis is associated with higher affective adaptive reactions that tend to normalize during the pregnancy, with overall preserved maternal fetal representations of attachment.
Wissam El-Hage; Julie Léger; Aude Delcuze; Bruno Giraudeau; Franck Perrotin
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-07-25
Journal Detail:
Title:  PloS one     Volume:  7     ISSN:  1932-6203     ISO Abbreviation:  PLoS ONE     Publication Date:  2012  
Date Detail:
Created Date:  2012-07-31     Completed Date:  2013-04-09     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  101285081     Medline TA:  PLoS One     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e41777     Citation Subset:  IM    
Clinique Psychiatrique Universitaire, CHRU de Tours, France.
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MeSH Terms
Amniocentesis / adverse effects,  psychology*
Anxiety / diagnosis,  etiology
Depression / diagnosis,  etiology
Fetus / metabolism
Maternal Behavior / psychology*
Mothers / psychology*
Pregnancy Complications / diagnosis,  etiology
Prenatal Diagnosis
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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