Document Detail

Amisulpride augmentation after the failure of citalopram for depression: a case report.
MedLine Citation:
PMID:  17286793     Owner:  NLM     Status:  MEDLINE    
This case report describes a 35-year-old woman with a first depressive episode. She was treated with the serotonergic antidepressant citalopram for 12 weeks without therapeutic response. Low-dose amisulpride augmentation resulted in a significant clinical improvement. We hypothesize that the dopaminergic properties of amisulpride might augment the effects of serotonergic antidepressants in refractory patients.
A F Carvalho; P R Nunes-Neto; J L Cavalcante; M C Oliveira Lima
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical pharmacy and therapeutics     Volume:  32     ISSN:  0269-4727     ISO Abbreviation:  J Clin Pharm Ther     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-02-08     Completed Date:  2007-04-17     Revised Date:  2008-05-28    
Medline Journal Info:
Nlm Unique ID:  8704308     Medline TA:  J Clin Pharm Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  97-9     Citation Subset:  IM    
Department of Clinical Medicine, Psychiatry Outpatient Clinics, Federal University of Ceará, Fortaleza, CE, Brazil.
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MeSH Terms
Citalopram / administration & dosage,  therapeutic use*
Depression / drug therapy*
Dopamine Antagonists / therapeutic use*
Drug Therapy, Combination
Serotonin Uptake Inhibitors / administration & dosage,  therapeutic use*
Sulpiride / analogs & derivatives*,  therapeutic use
Treatment Failure
Reg. No./Substance:
0/Dopamine Antagonists; 0/Serotonin Uptake Inhibitors; 15676-16-1/Sulpiride; 53583-79-2/sultopride; 59729-33-8/Citalopram

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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