Document Detail


Amiodarone induced torsades de pointes with excessive QT dispersion following quinidine induced polymorphic ventricular tachycardia.
MedLine Citation:
PMID:  9309756     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of amiodarone induced torsades de pointes (TdP) associated with increase QT dispersion in a patient with a history of quinidine induced TdP. An increase in QT dispersion of > 100% was noted on the 12 lead surface ECG postamiodarone therapy. In summary, amiodarone has a potential to induce TdP in patients with a previous history of quinidine induced TdP. QT dispersion could be a potential marker of TdP in these patients.
Authors:
H T Tran; M S Chow; J Kluger
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  20     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-11-06     Completed Date:  1997-11-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2275-8     Citation Subset:  IM    
Affiliation:
Division of Cardiovascular Therapeutics, Hartford Hospital, Connecticut 06102-5037, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amiodarone / adverse effects*,  therapeutic use
Anti-Arrhythmia Agents / adverse effects*,  therapeutic use
Electrocardiography*
Electrocardiography, Ambulatory
Female
Humans
Quinidine / adverse effects*,  therapeutic use
Tachycardia, Ventricular / chemically induced*,  diagnosis
Torsades de Pointes / chemically induced*,  diagnosis
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 1951-25-3/Amiodarone; 56-54-2/Quinidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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