| Amiodarone-induced intra-His block. | |
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MedLine Citation:
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PMID: 6736449 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two patients, one with and one without preexisting conduction system abnormalities, were treated with amiodarone for refractory ventricular arrhythmias. Electrophysiologic testing before and during amiodarone therapy revealed amiodarone-induced HV interval prolongation and second degree intra-His Wenckebach block with no change in QRS configuration during atrial pacing at relatively long cycle lengths. The mechanism responsible for this phenomenon is unclear. These cases illustrate that amiodarone can induce distal conduction system block even in the absence of clinical conduction system disease in a pattern that mimics atrioventricular nodal block. |
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Authors:
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E E Kennedy; W P Batsford |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of the American College of Cardiology Volume: 4 ISSN: 0735-1097 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 1984 Jul |
Date Detail:
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Created Date: 1984-07-27 Completed Date: 1984-07-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 192-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Amiodarone / adverse effects* Arrhythmias, Cardiac / drug therapy, physiopathology Atrioventricular Node / drug effects, physiopathology Benzofurans / adverse effects* Bundle of His / drug effects*, physiopathology Electrocardiography Heart Block / chemically induced*, physiopathology Heart Conduction System / drug effects* Humans Male |
| Chemical | |
Reg. No./Substance:
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0/Benzofurans; 1951-25-3/Amiodarone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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