Document Detail


Amiodarone as treatment for atrial tachycardias after surgery.
MedLine Citation:
PMID:  9272524     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Atrial flutter, including all types of postoperative atrial tachycardias, is the one with the highest risk of late sudden death. Thus, late postoperative atrial tachycardias must be suppressed and all patients should be permanently treated after a first episode of atrial flutter. Daily oral doses of 200-250 mg/m2 amiodarone were found to be highly effective and well tolerated in young patients. However, in older patients and after long-term therapy, its use is restricted by adverse side-effects. In these cases, association of lower doses of antiarrhythmic agents, including amiodarone, may be effective and well tolerated. The use of other therapeutic options such as radiofrequency ablation should also be considered in older patients having drug-refractory postoperative atrial flutter.
Authors:
E Villain
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  20     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-10-16     Completed Date:  1997-10-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2130-2     Citation Subset:  IM    
Affiliation:
Hôpital Necker, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adolescent
Adult
Amiodarone / administration & dosage,  adverse effects,  therapeutic use*
Anti-Arrhythmia Agents / administration & dosage,  adverse effects,  therapeutic use*
Atrial Flutter / drug therapy*,  etiology,  surgery
Catheter Ablation
Child
Child, Preschool
Death, Sudden, Cardiac / etiology,  prevention & control
Drug Combinations
Follow-Up Studies
Heart Defects, Congenital / surgery
Humans
Infant
Longitudinal Studies
Lung Diseases, Interstitial / chemically induced
Photosensitivity Disorders / chemically induced
Postoperative Complications / drug therapy*,  surgery
Risk Factors
Tachycardia / etiology
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 0/Drug Combinations; 1951-25-3/Amiodarone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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