| Aminoglycosides enhance the adherence of Staphylococcus aureus to HeLa cells. | |
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MedLine Citation:
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PMID: 2775357 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sub-lethal concentrations of aminoglycosides enhanced the adherence of Staphylococcus aureus FDA 209P to HeLa cells, whereas beta-lactams, pyridone carboxylic acid derivatives and chloramphenicol did not. Treatment with aminoglycosides also enhanced the bacterial adherence of these cells to immobilized fibronectin and laminin, and changed the bacterial cell surface to a more hydrophilic state than exists in non-treated cells. The adherence of S. aureus was not inhibited by lipoteichoic acid, extracted from the same strain, regardless of whether the bacterial cells were treated with an aminoglycoside or not. No correlation was observed between the adherence and zeta-potential of S. aureus. |
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Authors:
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Y Miyake; A Kohada; I Fujii; M Sugai; H Suginaka |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of antimicrobial chemotherapy Volume: 23 ISSN: 0305-7453 ISO Abbreviation: J. Antimicrob. Chemother. Publication Date: 1989 Jan |
Date Detail:
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Created Date: 1989-08-23 Completed Date: 1989-08-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7513617 Medline TA: J Antimicrob Chemother Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 79-86 Citation Subset: IM |
Affiliation:
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Department of Microbiology, Hiroshima University School of Dentistry, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aminoglycosides Anti-Bacterial Agents / pharmacology* Bacterial Adhesion / drug effects* Hela Cells Humans Staphylococcus aureus / physiology* |
| Chemical | |
Reg. No./Substance:
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0/Aminoglycosides; 0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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