| AMINO GROUP FORMATION AND GLUTAMATE SYNTHESIS IN STREPTOCOCCUS BOVIS. | |
| | |
MedLine Citation:
|
PMID: 14219016 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Burchall, J. J. (University of Illinois, Urbana), R. A. Niederman, and M. J. Wolin. Amino group formation and glutamate synthesis in Streptococcus bovis. J. Bacteriol. 88:1038-1044. 1964.-Extracts of Streptococcus bovis grown on NH(4) (+) as a nitrogen source contain a nicotinamide adenine dinucleotide phosphate (NADP)-linked glutamic dehydrogenase and are devoid of alanine dehydrogenase, other amino acid dehydrohygenases, and aspartase. A potential source of reduced nicotinamide adenine dinucleotide phosphate for glutamate synthesis is a NADP and nicotinamide adenine dinucleotide (NAD)-linked glyceraldehyde-3-phosphate dehydrogenase present in the extracts. Experiments with C(14)-labeled glucose and NaHCO(3) indicate that the glutamate carbon skeleton is synthesized by a tricarboxylic acid pathway. The synthesis of the carbon skeleton of glutamate is repressed when glutamate or casein hydrolysate supplement the NH(4) (+)-containing growth medium. Repression of glutamic dehydrogenase and a NAD-linked isocitric dehydrogenase occurs only when complex nitrogen sources, but not when free amino acids, are added to the growth medium. |
| | |
Authors:
|
J J BURCHALL; R A NIEDERMAN; M J WOLIN |
Related Documents
:
|
10512566 - The neurochemical basis of learning and neurocomputation: the redox theory. 19363596 - The importance of myocardial amino acids during ischemia and reperfusion in dilated lef... 1099096 - Aspartate transcarbamylase of escherichia coli. mechanisms of inhibition and activation... 7575436 - Arsenite release on enzymic transformation of arsonomethyl substrate analogues: a poten... 23528296 - Arylpiperazines as fatty acid transport protein 1 (fatp1) inhibitors with improved pote... 6601226 - Alteration in membrane permeability by diacylglycerol and phosphatidylcholine containin... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of bacteriology Volume: 88 ISSN: 0021-9193 ISO Abbreviation: J. Bacteriol. Publication Date: 1964 Oct |
Date Detail:
|
Created Date: 1965-02-01 Completed Date: 1996-12-01 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 2985120R Medline TA: J Bacteriol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1038-44 Citation Subset: OM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Asparagine* Aspartic Acid* Caseins* Glutamate Dehydrogenase* Glutamates* Glyceraldehyde-3-Phosphate Dehydrogenases* Isocitrate Dehydrogenase* Metabolism* NADP* Nucleotides* Research* Streptococcus* |
| Chemical | |
Reg. No./Substance:
|
0/Caseins; 0/Glutamates; 0/Nucleotides; 53-59-8/NADP; 56-84-8/Aspartic Acid; 7006-34-0/Asparagine; EC 1.1.1.41/Isocitrate Dehydrogenase; EC 1.2.1.-/Glyceraldehyde-3-Phosphate Dehydrogenases; EC 1.4.1.2/Glutamate Dehydrogenase |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: NATURE OF THE LABILE IMMUNOGENIC SUBSTANCE IN THE PARTICULATE FRACTION ISOLATED FROM MYCOBACTERIUM T...
Next Document: CATALASE ACTIVITY IN LEPTOSPIRA.