Document Detail


Amino acid transport in human ciliary epithelium.
MedLine Citation:
PMID:  696265     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A statistical study of the co-variation of the concentrations of 19 amino acids and related compounds from 21 persons was performed as a factor analysis of Caq/Cpl and of Caq. Six factors explained about 83% of the observed variation. Factor 1 showed a correlation to alpha-amino-N-butyric acid, valine, methionine, isoleucine, leucine, tyrosine and phenylalanine, factor 2 to lysine, histidine, arginine and glutamine (containing serine), factor 3 to taurine and proline, factor 4 to glycine and cystine, factor 5 to urea and factor 6 to glutamic acid. Only alanine and threonine showed a correlation to different factors in the Caq/Cpl- and the Caq-matrix. This correlation of groups of substances to different and independent factors is considered to be an argument in favour of the existence of six transport systems in the ciliary epithelium for the investigated substances.
Authors:
N Ehlers; K Kristensen; F Schønheyder
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta ophthalmologica     Volume:  56     ISSN:  0001-639X     ISO Abbreviation:  Acta Ophthalmol (Copenh)     Publication Date:  1978 Oct 
Date Detail:
Created Date:  1978-11-29     Completed Date:  1978-11-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370347     Medline TA:  Acta Ophthalmol (Copenh)     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  777-84     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / blood,  metabolism*
Aqueous Humor / analysis
Biological Transport, Active
Ciliary Body / metabolism*
Epithelium / metabolism*
Factor Analysis, Statistical
Humans
Chemical
Reg. No./Substance:
0/Amino Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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