| Amino acid sensing mechanisms: an Achilles heel in cancer? | |
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MedLine Citation:
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PMID: 22686629 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The act of increasing in mass, either in non-dividing cells or in dividing cells seeking to provide new material for daughter cells depends upon the continued presence of extracellular nutrients in order to conserve mass. For amino acid nutrients it appears that their insufficiency to promote new protein synthesis is actively monitored by both prokaryotic and eukaryotic cells, eliciting appropriate cellular responses that may depend not only on bulk nutrient supply, but also on the abundance of specific amino acids. |
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Authors:
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Richard F Lamb |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-11 |
Journal Detail:
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Title: The FEBS journal Volume: - ISSN: 1742-4658 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-6-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101229646 Medline TA: FEBS J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 The Authors Journal compilation © 2012 FEBS. |
Affiliation:
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Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Ave, Edmonton, Alberta, Canada T6G 1Z2. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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