Document Detail

Amino acid losses in ileostomy fluid on a protein-free diet.
MedLine Citation:
PMID:  8279406     Owner:  NLM     Status:  MEDLINE    
The contribution of losses via the gastrointestinal tract to maintenance amino acid requirements was assessed by collecting the ileostomy fluid of volunteers given a protein-free diet for 5 d. The subjects were eight adult men and women with terminal ileum ileostomies after ulcerative colitis. Four consecutive 24-h collections of both digesta and urine were made. On the last 2 d an antibiotic was given that suppressed microbial activity in the digesta and slightly reduced ileostomy outflow. Mean daily amino acid excretion in ileostomy fluid ranged from 32 mg/d for methionine to approximately 330 mg/d for aspartate and glutamate. These losses were compared with current international estimates of amino acid requirements. For most essential amino acids gastrointestinal losses accounted for 14-33% of daily maintenance requirements but for threonine the contribution was 61%.
M F Fuller; A Milne; C I Harris; T M Reid; R Keenan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  59     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1994 Jan 
Date Detail:
Created Date:  1994-02-07     Completed Date:  1994-02-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  70-3     Citation Subset:  AIM; IM    
Rowett Research Institute, Bucksburn, Aberdeen, UK.
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MeSH Terms
Amino Acids / metabolism*
Body Fluids / metabolism
Dietary Proteins / administration & dosage*
Digestive System / metabolism
Middle Aged
Reg. No./Substance:
0/Amino Acids; 0/Dietary Proteins

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