| Amino acid ingestion and glucose metabolism--a review. | |
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MedLine Citation:
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PMID: 20882645 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Interest in the effect of proteins or amino acids on glucose metabolism dates back at least a century, largely because it was demonstrated that the amino acids from ingested protein could be converted into glucose. Indeed, these observations influenced the dietary information provided to people with diabetes. Subsequently it was shown that ingested protein did not raise the blood glucose concentration. It also was shown that proteins could stimulate a rise in insulin and glucagon but the response to various proteins was different. In addition, it was shown that individual amino acids also could stimulate a rise in insulin and in glucagon concentrations. When individual amino acids are ingested by normal subjects, there is an ordering of the insulin and glucagon responses. However, the order is not the same for insulin and glucagon. In addition, the metabolic response cannot be predicted based on the functional groups of the amino acids. Thus, empirical prediction of the metabolic response to ingested single amino acids is not possible. |
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Authors:
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Mary C Gannon; Frank Q Nuttall |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: IUBMB life Volume: 62 ISSN: 1521-6551 ISO Abbreviation: IUBMB Life Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-30 Completed Date: 2011-01-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888706 Medline TA: IUBMB Life Country: England |
Other Details:
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Languages: eng Pagination: 660-8 Citation Subset: IM |
Copyright Information:
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© 2010 IUBMB IUBMB Life. |
Affiliation:
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Metabolic Research Laboratory, Section of Endocrinology, Metabolism & Nutrition VA Medical Center, Departments of Medicine, University of Minnesota, Minneapolis, Minnesota 55417, USA. ganno004@umn.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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metabolism* Dietary Proteins / metabolism* Glucose / metabolism* Humans |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Dietary Proteins; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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