| Amino acid concentration in plasma after gastro-intestinal, intraportal and intravenous administration of crystalline amino acids. Preliminary report. | |
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MedLine Citation:
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PMID: 822665 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In three series of 3 dogs each a solution of crystalline amino acids (Vamin) was given by different routes: gastro-intestinally, intraportally of intravenously. The infusion period was 3 hours and the administered amount 3 g per kg body weight. The amino acid concentration in plasma from different sites of the circulation was analysed before, during and after the infusion. In the series of intraportal and of intravenous infusion blood was taken from the hepatic vein and a peripheral vein and in the gastro-intestinal series from the portal vein as well. Tryptophan and tyrosine increased very slightly in all the series and tyrosine also showed a tendency to decrease during the infusion after an initial rise. Glutamic acid and aspartic acid increased quite markedly when given intravenously and intraportally, but there were only very small blood-level changes at gastro-intestinal administration. The intestinal mucosa seems to play an important role in amino acid metabolism. The remaining 14 of the 18 amino acids given showed approximately the same pattern of blood-level changes during and after the infusion. |
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Authors:
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S Bark |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta chirurgica Scandinavica Volume: 142 ISSN: 0001-5482 ISO Abbreviation: Acta Chir Scand Publication Date: 1976 |
Date Detail:
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Created Date: 1976-10-29 Completed Date: 1976-10-29 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7906530 Medline TA: Acta Chir Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 279-84 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
/
administration & dosage,
blood*,
metabolism Animals Aspartic Acid / blood, metabolism Dogs Glutamates / blood, metabolism Injections Intestinal Mucosa / metabolism Leucine / blood, metabolism Liver / metabolism Parenteral Nutrition* Portal Vein Stomach Tryptophan / blood, metabolism Tyrosine / blood, metabolism |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Glutamates; 55520-40-6/Tyrosine; 56-84-8/Aspartic Acid; 61-90-5/Leucine; 73-22-3/Tryptophan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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