Document Detail


Amino acid concentration in plasma after gastro-intestinal, intraportal and intravenous administration of crystalline amino acids. Preliminary report.
MedLine Citation:
PMID:  822665     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In three series of 3 dogs each a solution of crystalline amino acids (Vamin) was given by different routes: gastro-intestinally, intraportally of intravenously. The infusion period was 3 hours and the administered amount 3 g per kg body weight. The amino acid concentration in plasma from different sites of the circulation was analysed before, during and after the infusion. In the series of intraportal and of intravenous infusion blood was taken from the hepatic vein and a peripheral vein and in the gastro-intestinal series from the portal vein as well. Tryptophan and tyrosine increased very slightly in all the series and tyrosine also showed a tendency to decrease during the infusion after an initial rise. Glutamic acid and aspartic acid increased quite markedly when given intravenously and intraportally, but there were only very small blood-level changes at gastro-intestinal administration. The intestinal mucosa seems to play an important role in amino acid metabolism. The remaining 14 of the 18 amino acids given showed approximately the same pattern of blood-level changes during and after the infusion.
Authors:
S Bark
Related Documents :
7995185 - Amino acid derivatives of 5-asa as novel prodrugs for intestinal drug delivery.
6696935 - Glycosphingolipid patterns of the epithelial and non-epithelial compartments of rat lar...
1328345 - Intestinal fuels: glutamine, short-chain fatty acids, and dietary fiber.
10330055 - Angiotensin ii inhibits hco-3 absorption via a cytochrome p-450-dependent pathway in mtal.
20162155 - A simple explanation of the enhancement or depletion of the enantiomeric excess in the ...
11486605 - Cytotoxic bicyclic diterpene from the brown alga sargassum crispum.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta chirurgica Scandinavica     Volume:  142     ISSN:  0001-5482     ISO Abbreviation:  Acta Chir Scand     Publication Date:  1976  
Date Detail:
Created Date:  1976-10-29     Completed Date:  1976-10-29     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7906530     Medline TA:  Acta Chir Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  279-84     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amino Acids / administration & dosage,  blood*,  metabolism
Animals
Aspartic Acid / blood,  metabolism
Dogs
Glutamates / blood,  metabolism
Injections
Intestinal Mucosa / metabolism
Leucine / blood,  metabolism
Liver / metabolism
Parenteral Nutrition*
Portal Vein
Stomach
Tryptophan / blood,  metabolism
Tyrosine / blood,  metabolism
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Glutamates; 55520-40-6/Tyrosine; 56-84-8/Aspartic Acid; 61-90-5/Leucine; 73-22-3/Tryptophan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Periodic structure of physiologic and pathologic tremor
Next Document:  The development of a radioimmunoassay for arginine vasopressin.