Document Detail


Amino acid composition of proteoglycan protein of human articular cartilage in normal conditions and in degeneration
MedLine Citation:
PMID:  6438853     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Proteoglycan protein of human articular cartilage is found to contain a considerable amount of leucine, proline, glutaminic acid and glycine. The amino acid composition of various proteoglycan fractions differs in the methionine content. Proteoglycan protein from the degeneratively changed cartilage contains a less amount of lysine and serine. It is supposed that the found changes may be induced by the atypical synthesis of the proteoglycan protein shaft by chondrocytes under the cartilage degeneration.
Authors:
D V Kosiagin
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Ukrainskiĭ biokhimicheskiĭ zhurnal     Volume:  56     ISSN:  0201-8470     ISO Abbreviation:  Ukr. Biokhim. Zh.     Publication Date:    1984 Sep-Oct
Date Detail:
Created Date:  1985-01-18     Completed Date:  1985-01-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7804246     Medline TA:  Ukr Biokhim Zh     Country:  USSR    
Other Details:
Languages:  rus     Pagination:  549-51     Citation Subset:  IM    
Vernacular Title:
Aminokislotnyĭ sostav belka proteoglikanov sustavnogo khriashcha cheloveka v norme i pri degeneratsii.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / analysis*
Cartilage Diseases / metabolism,  pathology
Cartilage, Articular / metabolism*,  pathology
Humans
Lysine / analysis
Proteoglycans / analysis*
Serine / analysis
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Proteoglycans; 56-45-1/Serine; 56-87-1/Lysine

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