Document Detail


Amino acid composition of human milk is not unique.
MedLine Citation:
PMID:  8027865     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine whether the amino acid pattern of human milk is unique, we compared the amino acid pattern of human milk with the amino acid patterns of the milks of great apes (chimpanzee and gorilla), lower primates (baboon and rhesus monkey) and nonprimates (cow, goat, sheep, llama, pig, horse, elephant, cat and rat). Amino acid pattern was defined as the relative proportion of each amino acid (protein-bound plus free) (in mg) to the total amino acids (in g). Total amino acid concentration was lower in primate milk than in nonprimate milk. There were commonalities in the overall amino acid pattern of the milks of all species sampled; the most abundant amino acids were glutamate (plus glutamine, 20%), proline (10%) and leucine (10%). Essential amino acids were 40%, branched-chain amino acids 20%, and sulfur amino acids 4% of the total amino acids. The amino acid pattern of human milk was more similar to those of great apes than to those of lower primates. For example, cystine was higher and methionine was lower in primate milks than in nonprimate milks, and in great ape and human milks than in lower primate milks. Because the milk amino acid patterns of the human and elephant, both slow-growing species, were dissimilar, the amino acid pattern of human milk seems unrelated to growth rate.
Authors:
T A Davis; H V Nguyen; R Garcia-Bravo; M L Fiorotto; E M Jackson; D S Lewis; D R Lee; P J Reeds
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of nutrition     Volume:  124     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-08-09     Completed Date:  1994-08-09     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1126-32     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / analysis*
Animals
Camelids, New World
Cats
Cattle
Elephants
Female
Goats
Gorilla gorilla
Horses
Humans
Macaca mulatta
Milk / chemistry*
Milk, Human / chemistry*
Pan troglodytes
Papio
Rats
Sheep
Species Specificity
Swine
Grant Support
ID/Acronym/Agency:
HV-53030/HV/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Amino Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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