Document Detail

Amino Acid Balance with Extended Daily Diafiltration in Acute Kidney Injury.
MedLine Citation:
PMID:  22652535     Owner:  NLM     Status:  Publisher    
Background: The impact of hybrid dialysis therapies on amino acid (AA) balance in critically ill patients with acute kidney injury is unknown. Methods: We examined prospectively the AA balance with extended daily diafiltration (EDDF). Results: We studied 7 patients. AA clearances with EDDF ranged from 21.6 ml/min (tryptophan) to 66.9 ml/min (taurine). AA loss was 4.2 (IQR 1.4-12.3) g/day and 4.5% of daily protein intake for patients on enteral nutrition (EN). Percentage AA loss per hour on EDDF was highest for glutamine (32.1%) and lowest for glutamic acid (0.8%). Blood AA levels correlated with corresponding EDDF losses. Median total nitrogen appearance was 25.0 (IQR 20.6-29.3) g/day for patients on EN. This resulted in a negative nitrogen balance of -10.7 (IQR -16.6 to -1.4) g/day, of which 6.5% was attributable to AA loss. Conclusions: AA loss with EDDF was limited, but with much individual variability, and contributed to a strongly negative daily nitrogen balance.
Horng Ruey Chua; Ian Baldwin; Nigel Fealy; Toshio Naka; Rinaldo Bellomo
Related Documents :
22734845 - Kinetic resolution of secondary alcohols by the combination of a chiral brønsted acid,...
8657755 - Reduction of ach-induced contraction of rat isolated ileum by coptisine, (+)-caffeoylma...
16124775 - Cimipronidine, a cyclic guanidine alkaloid from cimicifuga racemosa.
15974615 - Triterpenoid saponin anthranilates from albizia grandibracteata leaves ingested by prim...
1352445 - Amino acid composition of dentine in permanent human teeth.
6746655 - Halobacterium volcanii trnas. identification of 41 trnas covering all amino acids, and ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-31
Journal Detail:
Title:  Blood purification     Volume:  33     ISSN:  1421-9735     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-6-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402040     Medline TA:  Blood Purif     Country:  -    
Other Details:
Languages:  ENG     Pagination:  292-299     Citation Subset:  -    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
Department of Intensive Care, Austin Hospital, Melbourne, Vic., Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Mutation in RAB33B, which encodes a regulator of retrograde Golgi transport, defines a second Dyggve...
Next Document:  The neural correlates of maternal sensitivity: An fMRI study.