| Amiel-Tison Neurological Assessment at term age: clinical application, correlation with other methods, and outcome at 12 to 15 months. | |
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MedLine Citation:
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PMID: 15686285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aims of this study were: (1) to perform the Amiel-Tison Neurological Assessment (ATNA) in a group of infants with different risk factors for brain damage; (2) to analyze the results of the examinations in light of the risk factors and presumed aetiology; (3) to compare results of examinations with results of cranial ultrasound, electroencephalography (EEG), and cerebral function monitoring (CFM); and (4) to evaluate neurological outcome at 12 to 15 months of age using the Amiel-Tison and Gosselin method, and developmental outcome using the Bayley Scales of Infant Development. Participants were 52 term, newborn infants (31 males, 21 females) with risk factors for brain damage. Mean birthweight was 3288g (SD 661g) and mean gestational age was 39.4wks (SD 1.2wks); range 38 to 41.3wks. Mean age at admission to a neonatal special care unit was 75h, (SD 13.7h). The group with a dynamic (evolving) clinical profile differed significantly from the group with a static (stable) profile in terms of aetiology, while the group with signs of prenatal brain damage differed from the group without these signs regarding aetiology and the level of severity of neurological signs. Sensitivity of the ATNA to detect infants with abnormal ultrasound was 0.97, with EEG 0.89, and with CFM 0.88. At follow-up at 12 to 15 months 47 children were examined: neurological examination was normal in 25 and five children had a minor, five a moderate, and 12 a severe neurological deficit. Agreement of the ATNA with neurological and developmental assessment at follow-up was very good. Our findings suggest that the ATNA is also of value in assessing aetiology and timing of brain lesions. |
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Authors:
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Darja Paro-Panjan; David Neubauer; Jana Kodric; Borut Bratanic |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Developmental medicine and child neurology Volume: 47 ISSN: 0012-1622 ISO Abbreviation: Dev Med Child Neurol Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-02-02 Completed Date: 2005-02-14 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0006761 Medline TA: Dev Med Child Neurol Country: England |
Other Details:
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Languages: eng Pagination: 19-26 Citation Subset: IM |
Affiliation:
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Neonatal Unit, Department of Child, Adolescent and Developmental Neurology, Division of Paediatrics, University Medical Centre, Ljubljana, Slovenia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain Damage, Chronic
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diagnosis*,
epidemiology,
etiology Echoencephalography Electroencephalography / statistics & numerical data Female Follow-Up Studies Humans Infant Infant, Newborn Male Neonatal Screening* Neurologic Examination / statistics & numerical data* Predictive Value of Tests Reproducibility of Results Risk Factors Statistics as Topic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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