| American Society of Clinical Oncology Clinical Practice Guideline Update on the Use of Chemotherapy Sensitivity and Resistance Assays. | |
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MedLine Citation:
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PMID: 21788567 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE To update the American Society of Clinical Oncology (ASCO) Technology Assessment guidelines on chemotherapy sensitivity and resistance assays (CSRAs) published in 2004. METHODS An Update Working Group reviewed data published between December 1, 2003, and May 31, 2010. MEDLINE and the Cochrane Library were searched. The literature search yielded 11,313 new articles. The limits for "human and English" were used, and then standard ASCO search strings for randomized controlled trials, meta-analyses, guidelines, and reviews were added, yielding 1,298 articles for abstract review. Of these, only 21 articles met predefined inclusion criteria and underwent full text review, and five reports of randomized controlled trials were included for data extraction. Results Review of the literature does not identify any CSRAs for which the evidence base is sufficient to support use in oncology practice. Recommendations The use of CSRAs to select chemotherapeutic agents for individual patients is not recommended outside of the clinical trial setting. Oncologists should make chemotherapy treatment recommendations based on published reports of clinical trials and a patient's health status and treatment preferences. Because the in vitro analytic strategy has potential importance, participation in clinical trials evaluating these technologies remains a priority. |
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Authors:
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Harold J Burstein; Pamela B Mangu; Mark R Somerfield; Deborah Schrag; David Samson; Lawrence Holt; Debra Zelman; Jaffer A Ajani |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-25 |
Journal Detail:
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Title: Journal of clinical oncology : official journal of the American Society of Clinical Oncology Volume: - ISSN: 1527-7755 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309333 Medline TA: J Clin Oncol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Harold J. Burstein and Deborah Schrag, Dana-Farber Cancer Institute, Boston, MA; Pamela B. Mangu and Mark R. Somerfield, American Society of Clinical Oncology, Alexandria, VA; David Samson, Blue Cross Blue Shield Association, Technology Evaluation Center, Chicago, IL; Lawrence Holt, Coastal Cancer Center, Myrtle Beach, SC; Debra Zelman, Debbie's Dream Foundation, Davie, FL; and Jaffer A. Ajani, The University of Texas MD Anderson Cancer Center, Houston, TX. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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