Document Detail


The American Brachytherapy Society recommendations for brachytherapy of soft tissue sarcomas.
MedLine Citation:
PMID:  11240245     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: This report presents the American Brachytherapy Society (ABS) guidelines for the use of brachytherapy for patients with soft tissue sarcoma. METHODS AND MATERIALS: Members of the ABS with expertise in soft tissue sarcoma formulated brachytherapy guidelines based upon their clinical experience and a review of the literature. The Board of Directors of the ABS approved the final report. RESULTS: Brachytherapy used alone or in combination with external beam irradiation is an established means of safely providing adjuvant local treatment after resection for soft tissue sarcomas in adults and in children. Brachytherapy options include low dose rate techniques with iridium 192 or iodine 125, fractionated high dose rate brachytherapy, or intraoperative high dose rate therapy. Recommendations are made for patient selection, techniques, dose rates, and dosages. Complications and possible interventions to minimize their occurrence and severity are reviewed. CONCLUSION: Brachytherapy represents an effective means of enhancing the therapeutic ratio, offering both biologic and dosimetric advantage in the treatment of patients with soft tissue sarcoma. The treatment approach used depends upon the institution, physician expertise, and the clinical situation. Guidelines are established for the use of brachytherapy in the treatment of soft tissue sarcomas in adults and in children. Practitioners and cooperative groups are encouraged to use these guidelines to formulate their treatment and dose-reporting policies. These guidelines will be modified, as further clinical results become available.
Authors:
S Nag; D Shasha; N Janjan; I Petersen; M Zaider;
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Publication Detail:
Type:  Guideline; Journal Article; Practice Guideline    
Journal Detail:
Title:  International journal of radiation oncology, biology, physics     Volume:  49     ISSN:  0360-3016     ISO Abbreviation:  Int. J. Radiat. Oncol. Biol. Phys.     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-03-12     Completed Date:  2001-03-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7603616     Medline TA:  Int J Radiat Oncol Biol Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1033-43     Citation Subset:  IM    
Affiliation:
Ohio State University, Columbus, OH, USA. nag.1@osu.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Brachytherapy / methods*,  standards
Child
Humans
Neoplasm Recurrence, Local / radiotherapy
Patient Selection
Radiotherapy Dosage
Sarcoma / radiography,  radiotherapy*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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