Document Detail

Amelogenesis imperfecta - a systematic literature review of associated dental and oro-facial abnormalities and their impact on patients.
MedLine Citation:
PMID:  18615322     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Amelogenesis imperfecta (AI) is a disease primarily affecting amelogenesis, but other aberrations have been reported. The purposes of this review were: (1) to identify other anomalies associated with AI, and (2) to describe the impact of the disease and its associated conditions on the oral health-related quality of life of patients, and the economic consequences. MATERIAL AND METHODS: A literature search was conducted in the following databases: PubMed, EMBASE,, The Cochrane Library, Web of Science, and OMIM, supplemented by a search for selected authors. Based on titles and abstracts, 137 papers were identified. RESULTS: Most articles were case reports or case series with few cases. Aberrations were reported in the eruption process, in the morphology of the crown, in the pulp-dentine organ, and in the number of teeth. Gingival conditions and oral hygiene were usually reported to be poor, and calculus was a common finding. Open bite was the most commonly reported malocclusion. A negative impact on patients' oral health-related quality of life was described, but information was scarce. No information was found on the economic impact. CONCLUSIONS: A number of aberrations associated with AI have been reported, but not sufficiently systematic to allow for a secondary analysis and synthesis of the findings. The impact on patients in terms of reduced quality of life and economic burden needs to be studied.
Sven Poulsen; Hans Gjørup; Dorte Haubek; Gro Haukali; Hanne Hintze; Henrik Løvschall; Marie Errboe
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Acta odontologica Scandinavica     Volume:  66     ISSN:  1502-3850     ISO Abbreviation:  Acta Odontol. Scand.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-14     Completed Date:  2008-08-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370344     Medline TA:  Acta Odontol Scand     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  193-9     Citation Subset:  D; IM    
Department of Pediatric Dentistry, School of Dentistry, Faculty of Health Sciences, University of Aarhus, Aarhus, Denmark.
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MeSH Terms
Amelogenesis Imperfecta / complications*,  economics,  psychology
Cost of Illness*
Malocclusion / complications
Periodontal Diseases / complications
Quality of Life*
Tooth Abnormalities / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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