Document Detail

Ameloblastomas: a regional Latin-American multicentric study.
MedLine Citation:
PMID:  17448213     Owner:  NLM     Status:  MEDLINE    
AIM: To classify 163 ameloblastoma cases according to the new WHO Classification of Odontogenic Tumours (2005) and analyse their clinical and microscopic features. METHODS: We studied the clinico-pathological features of 163 ameloblastoma cases from nine regional Latin-American institutions from Mexico and Guatemala. RESULTS: Ameloblastomas comprised 22.7% of all odontogenic tumours. The mean age was 41.4 years for solid ameloblastoma (SA) and 26.3 years for unicystic ameloblastoma (UA) (P < 0.001) and both sexes were almost equally affected. The mandible was mainly affected for both UA and SA. The mean size was 6.2 cm for SA and 6.3 cm for UA cases. The recurrence rate was 21.7% for SA and 12.6% for UA. UA was twice as more frequent than the solid variant. CONCLUSIONS: In this study we found that UA was frequently misdiagnosed as SA; however, there are enough clinical and microscopic features that allow for an accurate differentiation between both types of ameloblastoma that should be recognized for surgical and prognostic purposes. In this study, SA was not found in patients younger than 20 years, UA had a constant myxoid stroma while mature connective tissue was more frequently associated with the solid type.
C Ledesma-Montes; A Mosqueda-Taylor; R Carlos-Bregni; E Romero de León; J M Palma-Guzmán; C Páez-Valencia; A Meneses-García
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Oral diseases     Volume:  13     ISSN:  1354-523X     ISO Abbreviation:  Oral Dis     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-23     Completed Date:  2007-06-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508565     Medline TA:  Oral Dis     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  303-7     Citation Subset:  D    
Oral Pathology Laboratory, Facultad de Odontología, Universidad Nacional Autónoma de México, México, DF México.
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MeSH Terms
Age Factors
Ameloblastoma / classification*,  pathology*
Jaw Neoplasms / classification*,  pathology*
Neoplasm Recurrence, Local
Retrospective Studies

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