Document Detail

Ameloblastic fibrosarcoma of the mandible: report of two cases and review of the literature.
MedLine Citation:
PMID:  11334469     Owner:  NLM     Status:  MEDLINE    
Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic tumour. To date, 60 well-documented cases have been published in the English-language literature. Two additional cases located in the posterior region of the mandible are reported. The relevant clinicopathological features of these cases, as well as those previously reported are discussed. Approximately two-thirds of AFS are malignant tumors de novo, with an average age of the affected patients being 22.9 years. This age is lower than the one observed in AFS developing from a pre-existent benign lesion (mean 33 years). Although regional and distant metastases are very infrequent, AFS is a locally aggressive lesion, with 23 (37%) of the reported cases having at least one recurrence; 12 patients (19.3%) died of the disease. Wide surgical excision with long-term follow-up remains the treatment of choice for this neoplasm.
R C Bregni; A M Taylor; A M García
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology     Volume:  30     ISSN:  0904-2512     ISO Abbreviation:  J. Oral Pathol. Med.     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-03     Completed Date:  2001-08-02     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8911934     Medline TA:  J Oral Pathol Med     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  316-20     Citation Subset:  D; IM    
Facultad de Medicina, Universidad Francisco Marroquín, Guatemala City, Guatemala.
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MeSH Terms
Mandibular Neoplasms / pathology*
Odontogenic Tumors / pathology*

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