Document Detail


Ameloblastic carcinoma of the mandible.
MedLine Citation:
PMID:  9744469     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Ameloblastic carcinoma is a rare, aggressive odontogenic neoplasm of the jaws in which the epithelial cells exhibit cytologic features of recognizable ameloblastoma and malignancy. Cases with metastasis have been infrequently reported. METHODS: A case of a 64-year-old white woman with mandibular ameloblastic carcinoma with documented distant metastasis is presented. The patient's presenting symptoms included facial asymmetry of the right jaw over 2 months and the development of moderate trismus. Clinical manifestations, pathology, treatment, and biologic behavior are discussed. The nomenclature and classification of odontogenic carcinomas are reviewed, including entities that should be considered in the differential diagnosis. RESULTS: The patient underwent surgical resection consisting of mandibulectomy, parotidectomy, and modified radical neck dissection followed by radiation to both necks and tumor bed. Postsurgically, the patient developed pulmonary metastasis at 11 months and expired with widespread metastatic disease at 28 months. CONCLUSIONS: This case demonstrated an unusual behavior pattern in that local recurrence and regional metastasis did not occur. Distant metastasis occurred despite apparent adequate control of the primary mandibular tumor. The ameloblastic carcinoma is a highly malignant neoplasm which requires aggressive therapy. Prognosis is poor. Further reporting of ameloblastic carcinoma is encouraged.
Authors:
E J Simko; R B Brannon; D E Eibling
Related Documents :
19158529 - Marjolin ulcer arising within hidradenitis: a case report and literature review.
7995429 - Pilomatrix carcinoma: a case report and review of the literature.
199989 - Histologic variants of lipid-secreting carcinoma of the breast.
10418219 - Hepatocellular carcinoma presenting with acquired porphyria: a case report and review o...
20549899 - Small cell neuroendocrine carcinoma of the urinary bladder: report on two cases and rev...
1723839 - Solid adenosquamous carcinoma of the liver. a case report and review of the literature.
8464609 - Mucormycosis of the oral cavity.
2634729 - Acute primidone intoxication: report of a case.
19002049 - Diffuse alveolar hemorrhage with acute respiratory distress syndrome associated with ph...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Head & neck     Volume:  20     ISSN:  1043-3074     ISO Abbreviation:  Head Neck     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1998-11-18     Completed Date:  1998-11-18     Revised Date:  2006-10-05    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  654-9     Citation Subset:  IM    
Affiliation:
Otolaryngology Service, Langley Air Force Base, VA, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Female
Humans
Lung Neoplasms / secondary
Lymphatic Metastasis
Mandibular Neoplasms / pathology*
Middle Aged
Neoplasm Metastasis
Odontogenic Tumors / secondary*
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Primary malignant teratoma of the thyroid gland: report and discussion of two cases.
Next Document:  Single nucleotide polymorphism hunting in cyberspace.