Document Detail

Amelioration of cerebral ischemia by prior treatment of hypertension.
MedLine Citation:
PMID:  6771897     Owner:  NLM     Status:  MEDLINE    
Bilateral carotid artery ligation was made in 14 SHR while rCBF was serially measured with hydrogen clearance. Blood pressure was controlled with an intra-arterial catheter connected to a reservoir. There was no significant correlation between blood pressure and rCBF prior to the carotid occlusion, but afterwards there was a progressively increasingly negative correlation between mean arterial blood pressure and rCBF with time. These observations indicate that the severity of ischemia is greater in the presence of hypertension if the hypertension is present prior to the onset of ischemia and the blood pressure maintained constant thereafter.
J H Halsey; M O'Brien; E R Strong
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  11     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:    1980 May-Jun
Date Detail:
Created Date:  1980-09-23     Completed Date:  1980-09-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  235-40     Citation Subset:  IM    
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MeSH Terms
Blood Pressure
Brain Ischemia / therapy*
Carbon Dioxide / blood
Carotid Arteries
Hypertension / therapy*
Reg. No./Substance:
0/Hemoglobins; 124-38-9/Carbon Dioxide

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