Document Detail

Ambulatory oxygen in chronic heart failure.
MedLine Citation:
PMID:  1359262     Owner:  NLM     Status:  MEDLINE    
Ambulatory oxygen therapy may be of benefit in bicycle exercise tests. We have assessed the effects of ambulatory oxygen during walk tests in 12 patients with chronic heart failure. In 6 min walks with the patient breathing air, mean (SD) arterial oxygen saturation (SaO2) fell from 94.4 (3.7)% at rest to 90.1 (6.1)% (p = 0.014) on exercise. 21/min oxygen increased resting SaO2 from 93.7 (4.0)% (air cylinder) to 96.5 (3.0)% (p < 0.001) with no effect on minimum SaO2, distance, or breathlessness. During endurance walks, 4 l/min oxygen increased minimum SaO2 from 90.4 (5.6)% to 93.5 (4.7)% (p = 0.011) but also had no effect on breathlessness or distance. Ambulatory oxygen in currently available cylinders cannot be recommended for patients with chronic heart failure.
L J Restrick; S W Davies; L Noone; J A Wedzicha
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  340     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1992-12-17     Completed Date:  1992-12-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1192-3     Citation Subset:  AIM; IM    
Department of Thoracic Medicine, London Chest Hospital, UK.
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MeSH Terms
Ambulatory Care*
Chronic Disease
Exercise Test
Exercise Tolerance*
Heart Failure / blood,  metabolism,  therapy*
Middle Aged
Oxygen / blood
Oxygen Consumption
Oxygen Inhalation Therapy* / methods
Reg. No./Substance:

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