Document Detail

Ambulatory blood pressure monitoring: a critical review of the current methods to handle outliers.
MedLine Citation:
PMID:  1335007     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To examine the methods to handle marginal readings in the analysis of ambulatory blood pressure. DESIGN: Data obtained from automatic ambulatory blood pressure monitoring include several 'outliers', i.e. readings at the frontier of physiologically acceptable ranges. Several methods have been used to handle these readings. We need to know whether using different methods to reject outliers leads to different results in the analysis of the data. If so, then it is important that a common method be used by different authors. METHODS: Ten reported methods to handle outliers were selected and applied to a large set of unpublished blood pressure profiles (Novacor Diasys system). We compared the effects of data rejection by these methods on the mean values and standard deviations (calculated over 24 h, daytime and night-time) of the remaining data. RESULTS: The different methods had quite different effects on the same data set. Depending on the method used, the discarded data varied from 1 to 17% of the total number of readings. Among the rejected data, readings that occurred in the daytime varied from 14 to 56%. Also, 'high-value' outliers varied from 1 to 60% of the rejected data. On average over the total sample, the rejection of outliers had only a small effect on the mean values of blood pressure. In contrast, it may strongly reduce the standard deviation of the readings. CONCLUSION: The study emphasized the need to use a common method to handle outliers in the analysis of ambulatory blood pressure data.
L Berardi; N P Chau; X Chanudet; J Vilar; P Larroque
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of hypertension     Volume:  10     ISSN:  0263-6352     ISO Abbreviation:  J. Hypertens.     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1993-01-26     Completed Date:  1993-01-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1243-8     Citation Subset:  IM    
Unité de Recherches Biomathématiques et Biostatistiques, INSERM U263, Université Paris 7, France.
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MeSH Terms
Blood Pressure*
Blood Pressure Determination / methods*
Blood Pressure Monitors*
Data Interpretation, Statistical*
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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