Document Detail

Ambulatory blood pressure in prehypertensive children and adolescents.
MedLine Citation:
PMID:  22476249     Owner:  NLM     Status:  Publisher    
BACKGROUND: Prehypertension is defined as blood pressure (BP) ≥90th percentile, or ≥120/80 mmHg, but <95th percentile for age, sex, and height. Since the definition is made by conventional BP measurements and office BP can be quite variable, we studied whether prehypertension could be differentiated by ambulatory BP monitoring from normotension or hypertension (HTN) in children and adolescents. METHODS: One hundred and fifty-eight children (84 boys and 74 girls, aged 6-17 years, median 12) were studied. According to the office BP values, they were divided into normotension (80), prehypertension (20), and HTN (58). RESULTS: Systolic BP index and systolic daytime ambulatory BP (ABP) were significantly higher in prehypertensive patients than in normotensives and lower than hypertensives. When daytime ABP was used to diagnose HTN, four normotensive (5.0%), four prehypertensive (20.0%), and 27 hypertensive (46.6%) patients had HTN. Thus, in patients with prehypertension, the prevalence of masked HTN is significantly higher than in those with normotension. On the other hand, the prevalence of daytime ambulatory HTN is significantly lower, i.e., white-coat effect is more frequent, compared with hypertensive patients. CONCLUSION: Prehypertension lies between normotension and HTN in ABP values as well and is a good candidate for identifying masked HTN. Our data emphasize the importance of identifying prehypertension in children and adolescents.
Hisayo Fujita; Seiji Matsuoka; Midori Awazu
Related Documents :
19669669 - Pro-inflammatory cytokines of rat vasculature in doca-salt treatment.
20644699 - Salt restriction for the prevention of cardiovascular disease.
1621839 - Hemodynamic studies in doca-salt hypertensive rats after opening of an arteriovenous fi...
16284089 - Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mi...
2873909 - The role of the sympathetic nervous system in 2-kidney doca-hypertensive yucatan miniat...
9072349 - Endothelin-1 gene expression and vascular hypertrophy in doca-salt hypertension compare...
3393059 - An endogenous peptide that induces long-term blood pressure elevation.
2843199 - Antihypertensive efficacy of lisinopril. ambulatory blood pressure monitoring.
16377289 - Left atrial volume, geometry, and function in systolic and diastolic heart failure of p...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-5
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  -     ISSN:  1432-198X     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Pediatrics, Hiratsuka Kyosai Hospital, Kanagawa, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Infection, mutation, and cancer evolution.
Next Document:  The contribution of systematic reviews to the practice of pediatric nephrology.