| Ambulatory arterial stiffness index is unchanged in uncomplicated third-trimester singleton and twin pregnancies. | |
| | |
MedLine Citation:
|
PMID: 21501122 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Objective. To document the ambulatory arterial stiffness index (AASI) during pregnancy compared to three months after delivery in singleton and twin pregnancies. Design. Descriptive study with a follow-up design. Setting. University hospital in Eastern Finland. Population. 43 childbearing women; 32 with singleton and 11 with twin pregnancies. Methods. Ambulatory blood pressure measurements were conducted using a digital ambulatory blood pressure system. AASI was calculated as 1 minus the regression slope of diastolic on systolic blood pressures obtained from 24-hour monitoring. Main Outcome Measures. Arterial stiffness measured by AASI. Results. In normotensive pregnant women, the 95th percentiles of AASI were 0.40 in singleton and 0.46 in twin pregnancies, respectively, implying arterial normality and high elasticity. There were no differences in AASI values between singleton and twin pregnancies and no changes were observed postpartum. After delivery, but not during pregnancy, AASI correlated negatively with nocturnal systolic and diastolic blood pressure reduction (dipping) (r=-0.536, p=0.001; r=-0.674, p<0.001) and with maternal HDL (r=-0.363, p=0.038) and positively with maternal age (r=0.440, p=0.009), whereas maternal BMI had a significant impact on AASI both during and after pregnancy (r=0.366, p=0.016; r=0.377, p=0.028). Conclusions. Normal singleton or twin pregnancies had no detectable effects on AASI. However, pregnancy appeared to overcome the negative effects of low high-density lipoproteins, unfavorable dipping status and advanced maternal age on arterial stiffness, but not the effect caused by maternal body mass index. |
| | |
Authors:
|
Henna Kärkkäinen; Nonna Heiskanen; Heli Saarelainen; Pirjo Valtonen; Tiina Lyyra-Laitinen; Tomi Laitinen; Esko Vanninen; Seppo Heinonen |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Acta obstetricia et gynecologica Scandinavica Volume: 90 ISSN: 1600-0412 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-04-19 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: England |
Other Details:
|
Languages: eng Pagination: 516-23 Citation Subset: IM |
Copyright Information:
|
© 2011 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2011 Nordic Federation of Societies of Obstetrics and Gynecology. |
Affiliation:
|
Department of Obstetrics and Gynecology Department of Clinical Chemistry Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: HLA-A, HLA-B, and HLA-DRB1 allele distribution in a large Armenian population sample.
Next Document: Malpresentations - impact on mode of delivery.