| Ambulatory ECG-based T-wave alternans and heart rate turbulence predict high risk of arrhythmic events in patients with old myocardial infarction. | |
| | |
MedLine Citation:
|
PMID: 19838004 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Few studies have explored risk stratification of arrhythmic events in patients with ischemic heart diseases according to T-wave alternans (TWA) using modified moving average (MMA) method and heart rate turbulence (HRT). METHODS AND RESULTS: A retrospective analysis of 63 patients who underwent MMA-based TWA and HRT divided the patients into 3 groups: group-C of 21 controls, group-O of 21 patients with old myocardial infarction (OMI) showing no episodes of sustained ventricular tachyarrhythmia (SVT), and group-V of 21 OMI patients with episodes of SVT who received an implantable cardioverter-defibrillator. Among the 3 groups, positive TWA (>or=65 microV) and impaired HRT were observed most frequently in group-V (P<0.05). Using a logistic regression model, TWA yielded an odds ratio of 4.9 (95% confidence interval: 1.2-19.6, P<0.05), which was the only significant covariate for the incidence of life-threatening ventricular arrhythmias during a mean follow-up of 72 months. Conclusions: Patients with OMI showing episodes of SVT have a high risk for cardiac death because of abnormal repolarization and autonomic regulation. The analysis of MMA-based TWA and HRT can be a useful tool for predicting OMI patients at high risk of arrhythmic events. |
| | |
Authors:
|
Shingo Maeda; Mitsuhiro Nishizaki; Noriyoshi Yamawake; Takashi Ashikaga; Hiroshi Shimada; Mitsutoshi Asano; Kensuke Ihara; Tadashi Murai; Hidetoshi Suzuki; Hiroyuki Fujii; Harumizu Sakurada; Masayasu Hiraoka; Mitsuaki Isobe |
Related Documents
:
|
9397314 - Risk stratification prior to vascular surgery: does the location of a dipyridamole thal... 19674744 - Response to a cardiac event in relation to cardiac knowledge and risk perception in a l... 16298214 - Population-based study of event-rate, incidence, case fatality, and mortality for all a... 20429044 - Preoperative evaluation of patients with possible coronary artery disease. 15955194 - Cross-ventricular pacemaker-mediated tachycardia by myopotential induction during biven... 305234 - Prophylactic use of intra-aortic ballon pump in aortocoronary bypass for patients with ... |
Publication Detail:
|
Type: Journal Article Date: 2009-10-17 |
Journal Detail:
|
Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 73 ISSN: 1347-4820 ISO Abbreviation: Circ. J. Publication Date: 2009 Dec |
Date Detail:
|
Created Date: 2009-11-26 Completed Date: 2010-01-28 Revised Date: 2013-05-20 |
Medline Journal Info:
|
Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
|
Languages: eng Pagination: 2223-8 Citation Subset: IM |
Affiliation:
|
Department of Cardiology, Yokohama-Minami Kyosai Hospital, Yokohama, Japan. s-maeda@ja2.so-net.ne.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Death, Sudden, Cardiac / etiology*, prevention & control Defibrillators, Implantable Electrocardiography, Ambulatory* Female Heart Conduction System / physiopathology* Heart Rate* Humans Logistic Models Male Middle Aged Myocardial Infarction / complications*, mortality, physiopathology Odds Ratio Predictive Value of Tests Retrospective Studies Risk Assessment Risk Factors Tachycardia, Ventricular / diagnosis*, etiology, mortality, physiopathology, therapy Time Factors Ventricular Fibrillation / diagnosis*, etiology, mortality, physiopathology, therapy |
| Comments/Corrections | |
Comment In:
|
Circ J. 2010 Mar;74(3):594; author reply 595
[PMID:
20081318
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clinical Profiles of Hypertrophic Cardiomyopathy With Apical Phenotype.
Next Document: Risk of Smoking and Metabolic Syndrome for Incidence of Cardiovascular Disease.