Document Detail


Ambulatory 24-hr pH monitoring of esophagus, fundus, and antrum. A new technique for simultaneous study of gastroesophageal and duodenogastric reflux.
MedLine Citation:
PMID:  2384038     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A method for outpatient 24-hr simultaneous recording of pH in the distal esophagus, fundus, and antrum was developed in order to detect acid, alkaline, alkalacid gastroesophageal reflux, and duodenogastric reflux and to study these phenomena in patients complaining of gastroesophageal reflux and dyspepsia related symptoms. Two hundred ninety-four studies were performed in 42 healthy volunteers and 237 patients. Three-probe ambulatory 24-hr esophagogastric pH monitoring applicability, tolerability, and capability to determine a relationship between symptoms which occurred during the tests, gastroesophageal reflux, and duodenogastric reflux episodes were assessed. Eighty-nine percent of the three-probe esophagogastric pH studies were easily performed. The examination was tolerated well by 86.1% of the patients and poorly by 13.9%. A temporal correlation between symptoms and pH activities was recognized in 61.3% when the esophageal tracing was considered (acid gastroesophageal reflux recording) and in 95.6% when the three pH traces were simultaneously interpreted. Alkalacid gastroesophageal reflux and duodenogastric reflux total percentage times were significantly higher in patients complaining of dyspeptic symptoms than in patients only affected by typical gastroesophageal symptoms. Three-probe 24-hr ambulatory esophagogastric pH monitoring is a simple, well-tolerated test that should be routinely adopted for the study of patients complaining of unclear upper gastrointestinal tract symptomatology.
Authors:
S Mattioli; V Pilotti; V Felice; A Lazzari; R Zannoli; M L Bacchi; P Loria; A Tripodi; G Gozzetti
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  35     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-09-17     Completed Date:  1990-09-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  929-38     Citation Subset:  AIM; IM    
Affiliation:
Istituto di Clinica Chirurgica e Cardiochirurgia, Universitá di Bologna, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Circadian Rhythm / physiology*
Duodenogastric Reflux / diagnosis*,  physiopathology
Esophagus / physiopathology*
Female
Gastric Acidity Determination / instrumentation
Gastric Fundus
Gastroesophageal Reflux / diagnosis*,  physiopathology
Humans
Hydrogen-Ion Concentration
Male
Middle Aged
Monitoring, Physiologic / instrumentation,  methods
Pyloric Antrum
Stomach / physiopathology*
Comments/Corrections
Comment In:
Dig Dis Sci. 1991 Sep;36(9):1341-3   [PMID:  1760039 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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