Document Detail

Ambulatory 24-hour continuous electrocardiographic monitoring in 54 patients with ankylosing spondylitis.
MedLine Citation:
PMID:  2423334     Owner:  NLM     Status:  MEDLINE    
Of 54 patients with ankylosing spondylitis 48 were found to be HLA B27 positive. Ambulatory 24-hour Holter monitoring revealed electrocardiographic 'abnormalities' in 12 of the 48 HLA B27 positive patients. To our knowledge this is the first ambulatory Holter monitoring of a group of patients with ankylosing spondylitis, and the outcome seems to suggest a relationship between the tissue type HLA B27 and the occurrence of electrocardiographic 'abnormalities'. The frequency of atrioventricular block (types I and III) and atrial tachycardia was significantly higher in this group of patients than that found in similar studies of healthy adults. The frequency of psoriasis and cardiac murmurs was increased among the patients with electrocardiographic 'abnormalities'.
N H Thomsen; K Hørslev-Petersen; J M Beyer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European heart journal     Volume:  7     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-06-27     Completed Date:  1986-06-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  240-6     Citation Subset:  IM    
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MeSH Terms
Ambulatory Care
Arrhythmias, Cardiac / diagnosis*,  genetics
Bradycardia / diagnosis
Cardiac Complexes, Premature / diagnosis
Electrocardiography / methods*
HLA Antigens / genetics
HLA-B27 Antigen
Heart Atria
Heart Block / diagnosis
Heart Ventricles
Middle Aged
Spondylitis, Ankylosing / diagnosis*,  genetics
Tachycardia / diagnosis
Reg. No./Substance:
0/HLA Antigens; 0/HLA-B27 Antigen

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