| Ambient overnight hold of whole blood prior to the manufacture of blood components. | |
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MedLine Citation:
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PMID: 20667039 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Blood services routinely separate whole blood into components that are then stored under different conditions. The storage conditions used for whole blood prior to separation must therefore be a compromise between the needs of the red cells (which benefit from refrigeration) and plasma and platelets (which are better preserved at ambient temperature). For many years, the approach has been to manufacture plasma and platelet components on the day of blood collection, and to refrigerate any unprocessed blood for manufacture into red cell components on the following day. However, this can make it challenging to maintain adequate stocks of all components. The European practice of 'ambient hold' of whole blood for up to 24 hours prior to processing allows greater flexibility in blood component manufacture, and the data reviewed suggest there is relatively little impact on the quality of red cell or plasma components, and an improvement in the quality of platelet components. |
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Authors:
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Stephen Thomas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Transfusion medicine (Oxford, England) Volume: 20 ISSN: 1365-3148 ISO Abbreviation: Transfus Med Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-10-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9301182 Medline TA: Transfus Med Country: England |
Other Details:
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Languages: eng Pagination: 361-8 Citation Subset: IM |
Copyright Information:
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© 2010 The Author. Transfusion Medicine © 2010 British Blood Transfusion Society. |
Affiliation:
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Components Development Laboratory, NHS Blood and Transplant, Brentwood, Essex, UK. stephen.thomas@nhsbt.nhs.uk |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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