Document Detail

Ambient air pollution and hypertensive disorder of pregnancy.
MedLine Citation:
PMID:  24022815     Owner:  NLM     Status:  Publisher    
BACKGROUND: Ambient air pollution has been implicated in the development of hypertensive disorders of pregnancy (HDP). However, evidence of the association between air pollution and HDP is still limited, and the effects of gaseous air pollutants on HDP and their time windows of exposure have not been well studied.
METHODS: We used the Florida birth registry data to investigate the associations between air pollutants (NO2, SO2, PM2.5, O3 and CO) and the risks of HDP in 22 041 pregnant women in Jacksonville, Florida, USA from 2004 to 2005. Further, we examined whether air pollution exposure during different time windows defined by trimesters and the entire pregnancy had different effects on HDP.
RESULTS: The single-pollutant logistic regression model showed that exposure to four pollutants during the full pregnancy period was significantly associated with prevalence of HDP after adjusting for covariates: NO2 (OR=1.21, 95% CI 1.09 to 1.35), PM2.5 (OR=1.24, 95% CI 1.08 to 1.43), SO2 (OR=1.13, 95% CI 1.01 to 1.25) and CO (OR=1.12, 95% CI 1.03 to 1.22) per IQR increase. Similar effects were observed when first trimester exposure to NO2, SO2 and CO, and second trimester exposures to PM2.5 were examined. Consistent results were confirmed in multiple-pollutant models.
CONCLUSIONS: This study suggests that exposure to high levels of air pollution during early pregnancy and the full gestational period was associated with increased prevalence of HDP in Florida, USA.
Xiaohui Xu; Hui Hu; Sandie Ha; Jeffrey Roth
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-9-10
Journal Detail:
Title:  Journal of epidemiology and community health     Volume:  -     ISSN:  1470-2738     ISO Abbreviation:  J Epidemiol Community Health     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-9-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909766     Medline TA:  J Epidemiol Community Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Epidemiology, College of Public Health and Health Professional and College of Medicine, University of Florida, , Gainesville, Florida, USA.
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