Document Detail

Alveolar haemorrhage with pleural effusion as a manifestation of epithelioid haemangioendothelioma.
MedLine Citation:
PMID:  1612160     Owner:  NLM     Status:  MEDLINE    
A 22 year old male was admitted with haemoptysis. A chest X-ray showed bilateral confluent alveolar infiltrates. Bronchoscopy revealed blood oozing from all bronchopulmonary segments. Open lung biopsy disclosed bilateral effusions and large necrotizing nodules with pleural adhesions. Histological examination showed tumour cells, which were negative to epithelial and embryogenic markers but positive to factor VIII. This confirmed the diagnosis of an epithelioid haemangioendothelioma. This rare tumour, usually has an indolent course, whereas in our case it was complicated by alveolar and intrapleural bleeding.
D Struhar; P Sorkin; J Greif; S Marmor; E Geller
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The European respiratory journal     Volume:  5     ISSN:  0903-1936     ISO Abbreviation:  Eur. Respir. J.     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-07-30     Completed Date:  1992-07-30     Revised Date:  2013-05-23    
Medline Journal Info:
Nlm Unique ID:  8803460     Medline TA:  Eur Respir J     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  592-3     Citation Subset:  IM    
Pulmonary and Allergic Diseases Institute, Ichilov Medical Center, Tel-Aviv, Israel.
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MeSH Terms
Factor VIII / analysis
Hemangioendothelioma / chemistry,  complications*,  diagnosis
Hemoptysis / etiology
Hemorrhage / etiology*
Lung Diseases / etiology
Lung Neoplasms / chemistry,  complications*,  diagnosis
Pleural Effusion / etiology*
Pulmonary Alveoli*
Tomography, X-Ray Computed
Tumor Markers, Biological / analysis
Reg. No./Substance:
0/Tumor Markers, Biological; 9001-27-8/Factor VIII

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